Trespassing cancer cells: ‘fingerprinting’ invasive protrusions reveals metastatic culprits

EMFs: breast cancer culprits?

-Six phenols [2(3)-t-butyl-4-hydroxyanisole (BHA), 2-t-butylphenol, 4-methoxyphenol, 4-methylmercaptophenol, t-butylhydroquinone and 2,6-di-tbutylphenol] previously shown to be inhibitors of benzo(a)pyrene-induced neoplasia, were examined for their ability to induce in vivo changes in hepatic mono-oxygenase and detoxication enzyme activities, and to act as mono-oxygenase inhibitors when added i...

Invasive leader cells: metastatic oncotarget

Invasion into surrounding tissues is the first step of metastasis, and an understanding of the molecular basis of the invasive process may suggest novel strategies for anti-metastatic therapy. Breast tumors typically invade as adherent groups of cells, a process known as collective invasion. In vivo, collective invasion occurs within a complex tissue environment and involves interactions among ...

Muscle-invasive and Metastatic Bladder Cancer

Introduction Publications concerning muscle-invasive and metastatic bladder cancer are mostly based on retrospective analysis, including some larger multicentre studies and well-designed controlled studies. The studies underpinning the current guidelines were identified through a systematic literature research using Medline, the Cochrane central register of systematic reviews, and reference lis...

Muscle invasive and metastatic bladder cancer.

Direct RNA sequencing mediated identification of mRNA localized in protrusions of human MDA-MB-231 metastatic breast cancer cells

BACKGROUND Protrusions of cancer cells conferrers a vital function for cell migration and metastasis. Protein and RNA localization mechanisms have been extensively examined and shown to play pivotal roles for the functional presence of specific protein components in cancer cell protrusions. METHODS To describe genome wide RNA localized in protrusions of the metastatic human breast cancer cell...